Vector computer memory bank contention

A number of vector supercomputers feature very large memories. Unfortunately the large capacity memory chips that are used in these computers are much slower than the fast central processing unit (CPU) circuitry. As a result, memory bank reservation times (in CPU ticks) are much longer than on previous generations of computers. A consequence of these long reservation times is that memory bank contention is sharply increased, resulting in significantly lowered performance rates. The phenomenon of memory bank contention in vector computers is analyzed using both a Markov chain model and a Monte Carlo simulation program. The results of this analysis indicate that future generations of supercomputers must either employ much faster memory chips or else feature very large numbers of independent memory banks

A comparison of the Cray-2 performance before and after the installation of memory pseudo-banking

A suite of 13 large Fortran benchmark codes were run on a Cray-2 configured with memory pseudo-banking circuits, and floating point operation rates were measured for each under a variety of system load configurations. These were compared with similar flop measurements taken on the same system before installation of the pseudo-banking. A useful memory access efficiency parameter was defined and calculated for both sets of performance rates, allowing a crude quantitative measure of the improvement in efficiency due to pseudo-banking. Programs were categorized as either highly scalar (S) or highly vectorized (V) and either memory-intensive or register-intensive, giving 4 categories: S-memory, S-register, V-memory, and V-register. Using flop rates as a simple quantifier of these 4 categories, a scatter plot of efficiency gain vs Mflops roughly illustrates the improvement in floating point processing speed due to pseudo-banking. On the Cray-2 system tested this improvement ranged from 1 percent for S-memory codes to about 12 percent for V-memory codes. No significant gains were made for V-register codes, which was to be expected

MEMS reagent and sample handling procedure: Feasibility of viral antibody detection by passive immune agglutination

An attempt was made to develop a test requiring no preadsorption steps for the assessment of antibodies to rubella and mumps viruses using the passive immune agglutination (PIA) method. Both rubella and mumps antigens and antibodies were prepared. Direct PIA tests, using rubella antigen-coated beads, and indirect PIA tests, using rubella antibody-coated beads, were investigated. Attempts, using either method, were unsuccessful. Serum interference along with nonspecific agglutination of beads by the rubella antigen resulted in no specific response under the test conditions investigated. A new, highly sensitive approach, the enzyme immunoassay (EIA) test system, is recommended to overcome the nonspecificity. This system is a logical outgrowth of some of the solid phase work done on MEMS and represents the next generation tests system that can be directly applied to early disease detection and monitoring

Cryogenic flux-concentrator

Flux concentrator has high primary to secondary coupling efficiency enabling it to produce high magnetic fields. The device provides versatility in pulse duration, magnetic field strengths and power sources

Distortion of the Magnetosphere During a Magnetic Storm on 30 September, 1961

Magnetosphere distortion during magnetic storm observed by Explorer XII satellit

An Evaluation of a Battery of Functional and Structural Tests as Predictors of Likely Risk of Progression of Age-Related Macular Degeneration.

Purpose: To evaluate the ability of visual function and structural tests to identify the likely risk of progression from early/intermediate to advanced AMD, using the Age-Related Eye Disease Study (AREDS) simplified scale as a surrogate for risk of progression. The secondary aim was to determine the relationship between disease severity grade and the observed functional and structural deficits. Methods: A total of 100 participants whose AMD status varied from early to advanced were recruited. Visual function was assessed using cone dark adaptation, 14 Hz flicker and chromatic threshold tests and retinal structure was assessed by measuring drusen volume and macular thickness. The predictive value of the tests was estimated using ordinal regression analysis. Group comparisons were assessed using analysis of covariance. Results: Change in cone dark adaptation (cone τ) and yellow-blue (YB) chromatic sensitivity were independent predictors for AMD progression risk (cone τ, pseudo R2 = 0.35, P < 0.001; YB chromatic threshold, pseudo R2 = 0.16, P < 0.001). The only structural predictor was foveal thickness (R2 = 0.05, P = 0.047). Chromatic sensitivity and cone dark adaptation were also the best functional tests at distinguishing between severity groups. Drusen characteristics clearly differentiated between participants with early and advanced disease, but were not able to differentiate between those with early AMD and controls. Mean differences in retinal thickness existed between severity groups at the foveal (P = 0.040) and inner (P = 0.001) subfields. Conclusions: This study indicates that cone τ, YB chromatic threshold and foveal thickness are independent predictors of likely risk of AMD progression

On the Hα\alpha emission from the β\beta Cephei system

Be stars, which are characterised by intermittent emission in their hydrogen lines, are known to be fast rotators. This fast rotation is a requirement for the formation of a Keplerian disk, which in turn gives rise to the emission. However, the pulsating, magnetic B1IV star $\beta$ Cephei is a very slow rotator that still shows H$\alpha$ emission episodes like in other Be stars, contradicting current theories. We investigate the hypothesis that the H$\alpha$ emission stems from the spectroscopically unresolved companion of $\beta$ Cep. Spectra of the two unresolved components have been separated in the 6350-6850\AA range with spectro-astrometric techniques, using 11 longslit spectra obtained with ALFOSC at the Nordic Optical Telescope, La Palma. We find that the H$\alpha$ emission is not related to the primary in $\beta$ Cep, but is due to its 3.4 magnitudes fainter companion. This companion has been resolved by speckle techniques, but it remains unresolved by traditional spectroscopy. The emission extends from about $-$400 to +400 km s$^{-1}$. The companion star in its 90-year orbit is likely to be a classical Be star with a spectral type around B6-8. By identifying its Be-star companion as the origin of the H$\alpha$ emission behaviour, the enigma behind the Be status of the slow rotator $\beta$ Cep has been resolved.Comment: 4 pages, 3 figures. Accepted by A&A Letter

Complying With Feed Additive and Drug Withdrawl Periods

Most drugs are accumulated in excretory organs such as the kidneys and liver , and they are found in higher levels for a longer time in these organs than in other tissue. Due to a continuous excretion of the drugs from these organs, tissue levels are usually rapidly reduced after the drug is no longer fed or injected. The rate of excretion of a drug and its end products from animal tissues must be established before it can be considered for approval by the Food and Drug Administration. Then withdrawal periods that are sufficiently long enough to permit complete or near complete elimination of the drug from animal tissues , milk or eggs are established. Once a feed additive is approved it means that the FDA considers it completely safe for use in animal feeds without unsafe levels of residues occurring in the animal tis sue or its products if the withdrawal period is observed and it is fed at recommended levels

Higher-Order Corrections to Instantons

The energy levels of the double-well potential receive, beyond perturbation theory, contributions which are non-analytic in the coupling strength; these are related to instanton effects. For example, the separation between the energies of odd- and even-parity states is given at leading order by the one-instanton contribution. However to determine the energies more accurately multi-instanton configurations have also to be taken into account. We investigate here the two-instanton contributions. First we calculate analytically higher-order corrections to multi-instanton effects. We then verify that the difference betweeen numerically determined energy eigenvalues, and the generalized Borel sum of the perturbation series can be described to very high accuracy by two-instanton contributions. We also calculate higher-order corrections to the leading factorial growth of the perturbative coefficients and show that these are consistent with analytic results for the two-instanton effect and with exact data for the first 200 perturbative coefficients.Comment: 7 pages, LaTe